Bioanalytical CRO Service Provider
DMPK Assay CRO Service Provider
ADME CRO Assay Service Provider
Biomarker Analysis CRO Service Provider
CMC Analytical Stability Testing CRO Service Provider
With in depth knowledge of chemistry, chromatography, and mass spectrometry and extensive bioanalytical experience, Drumetix scientists are capable of developing bioanalytical methods for tough compounds in complex matrices. We are able to solve various problems encountered in method development, e.g., matrix suppression, adsorption to column or tubing (sticky compounds), carry-over, lack of functional groups for efficient ionization, interference, too hydrophilic to extract, etc.
Method validation is fully GLP compliant. Items covered in validation include intraday and interday precision and accuracy, specificity, ion suppression, extraction recovery, linearity of dilution and various stability tests (long-term frozen stability, freeze/thaw stability, stability of analyte in biological matrix at room temperature, stability of sample extract, and stock solution stability).